The cures for covid-19
The whole world is looking for a treatment, medicine or vaccine against the coronavirus. Researchers, upon completing the research phases required for each therapeutic proposal, must rely on the publication of the research with data that must be available to the scientific community, so that they can be adequately analyzed and validated. Science is evidence-based and this evidence has to be available to anyone trained in each area of research.
In the modern academic community, effective therapies have to support the evaluation of the different stages of the scientific method through a methodology that has historically characterized science, essential for obtaining new knowledge.
Any study in Russia, Brazil or Australia or in another country has to meet the universal requirements for researchers, which should be similar in all countries. Everything that is outside this dynamic of universities and research institutes has another orientation, not precisely within the objectives of science.
Appropriate and well-controlled clinical trials will ultimately determine the appropriate treatment modalities for COVID-19 and identify the stages of infection in which these treatments are effective, with what routes of administration, and with what dosage regimens.
This week, the Minister of People´s Power for Science, Technology and Innovation confirmed that IVIC researchers had found a “molecule”, called DR-10, that completely eliminates the coronavirus. According to press releases, it is a natural compound that inhibits the replication of the virus in cells grown in the laboratory and has in its composition ursolic acid (UA), which is found in various fruits (apple peels), vegetables, leaves of various plants (rosemary, lavender and thyme) and in some Chinese herbs.
Researchers from other countries have attributed and published the beneficial effects of UA as a dietary supplement, including anti-inflammatory, antioxidant, and anti-cancer effects. With these preliminary data, they have proposed it as an alternative medicine for the treatment and prevention of cancer, obesity / diabetes, cardiovascular and brain diseases, hepatitis, and muscle atrophy (sarcopenia).
The initial tests to evaluate future antiviral therapies are called in-vitro tests because they do not involve living beings, whether animals or humans. In the case of DR-10, there is no public data disclosed in an open way about in-vitro evaluations or those carried out in living beings, for their respective analysis. We look forward to publishing the experience for the rest of the similar researchers to share and analyze.
Many valuable drugs today originated from the study of popular culture home remedies, such as the antimalarial artemisinin. The scientific search for pharmacologically unique principles of existing remedies continues and they seek to complement the achievements of modern medicine.
A rapidly identified cure for the disease could be a known therapeutic drug that is reused to help resolve the pandemic situation. Artificial intelligence (AI) technology is being applied to identify marketed and non-marketed drugs with the potential to treat COVID-19. The list of potential drugs is long and they are currently being investigated in the world’s leading laboratories.
Scientific advances are not usually presented at press conferences or announced by political figures, but after they have appeared in trusted peer-reviewed publications. But this pandemic has changed many things and in first and third world countries this modality of political usufruct is becoming more frequent, not only in treatments but also in vaccines against the coronavirus.
Public spokespersons should not create an expectation of anticipated success about a possible cure for COVID-19. In some people, this can generate a false impression of security that can be translated into behaviors that increase the risk of being infected and infecting others with COVID-19, such as quarantine measures, use of masks and social distancing, the only measures non-pharmacological that can prevent the spread of the pandemic.
Originally published at www.elnacional.com on October 30, 2020.